In the Limelight: October 2020

Cover 17-5 October 2020

Persian-translation 17-5 October 2020

Centrosomes back in the limelight.

Centrosomes and centrioles were ‘born’ towards the end of the nineteenth century when they were first spotted and studied by astute cell and developmental biologists, including Edouard Van Beneden, as well as Theodor Boveri and Walther Fleming, who coined the terms ‘centrosome’ and ‘centriole’, respectively, that still designate these structures today. There was much initial excitement about ce...

Coronaviruses in the limelight.

Lysophospholipids in the limelight

Lysophosphatidic acid (LPA) is a serum phospholipid that evokes growth factor-like responses in many cell types through the activation of its G protein-coupled receptors. Although much is known about LPA signaling, it has remained unclear where and how bioactive LPA is produced. Umezu-Goto et al. (2002)(this issue, page 227) have purified a serum lysophospholipase D that generates LPA from lyso...